Computer programs for eukaryotic gene prediction

Computer programs for eukaryotic gene prediction

Seven popular programs for gene prediction in eukaryotic organisms are described and evaluated on the basis of availability for in-house and on-line use and prediction accuracy. This report outlines generally applicable approaches to computational gene prediction and known limitations in this field.

Eukaryotic Gene Prediction

Introduction: The advent of large-scale genome sequencing has revolutionized the field of genetics and biology. Sequencing projects require sophisticated computational analysis to manage vast collections of data. Scientists first sequenced a genome in 1977, that of a small bacteriophage consisting of 11 genes over 5.4kb of DNA. In the bacteriophage, coding genes comprise 95% of the genome. 1 Si...

Gnomon – NCBI eukaryotic gene prediction tool

Integrated databases and computer systems for studying eukaryotic gene expression

MOTIVATION The goal of the work was to develop a WWW-oriented computer system providing a maximal integration of informational and software resources on the regulation of gene expression and navigation through them. Rapid growth of the variety and volume of information accumulated in the databases on regulation of gene expression necessarily requires the development of computer systems for auto...

Unsupervised and semi-supervised training methods for eukaryotic gene prediction